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Fig. 6 | BMC Biology

Fig. 6

From: Single-cell spatial transcriptomic analysis reveals common and divergent features of developing postnatal granule cerebellar cells and medulloblastoma

Fig. 6

Developmental trajectories within GN lineage cells. a RNA velocities of GNs for Math1-GFP+ mouse at P7. b UMAP visualization of the transition probability of particular cells corresponding to four GN states. c The velocity-inferred root/end cells, velocity pseudotime, and cell cycle scores of P7 Math1-GFP+ mouse are shown. d Gene expression dynamics resolved along velocity pseudotime show a clear cascade of transcription of top likelihood-ranked TFs (likelihood > 0). e Driver genes are identified by high likelihoods. Expression dynamics along velocity pseudotime for the driver genes characterize their activity

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