Fig. 2

Genome and transcriptome conservation across Naegleria species. a Result of OrthoMCL analysis showing the number of orthogroups shared between the three N. fowleri strains and N. gruberi. The number of in-paralogue groups within each species is also shown (whereas strain-specific singletons are omitted from the diagram). The value 458 shown within the intersection of the three N. fowleri strains to the exclusion of N. gruberi is the number of orthogroups that did not retrieve any clear homolog in N. gruberi in a manual BLAST search. b Transcripts in the N. fowleri LEE transcriptome that share sequence similarity with genes in other Naegleria genomes based on BLAST analysis. Sequences with shared similarity are not considered to be necessarily orthologous