Fig 2

Morphological profiling of virus-infected cells. Overview of the phenomics approach. Cells are seeded in multiwell plates, incubated overnight followed by virus infection. Subsequently, virus-containing media is removed and compounds are added and incubated for 48h followed by fixation. Then, antibody staining and Cell Painting is performed, followed by high content imaging, image analysis and data analysis of the extracted phenotypic features (a more detailed description of the method can be found in Additional file 1 Figure S1c). Illustrations were partially created with BioRender.com