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Fig. 10 | BMC Biology

Fig. 10

From: FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells

Fig. 10

sVEGFR1-ex12 is a poor prognosis marker in squamous lung carcinoma patients. a, b Different sVEGFR1-exon12 usage value (exon expression value divided by gene expression value) between squamous lung carcinoma patients displaying low (<median, 1st and 2nd quartiles, n=243) and high (≥median, 3rd and 4th quartiles, n=244) FGF-2 (a) or FGFR1 (b) mRNA levels. Data is presented with mean ± SD. p values were calculated with an unpaired t test, ***p<0.001. c Overall survival analysis stratified according to sVEGFR1-exon12 usage value in squamous lung carcinoma patients for who clinical annotations were available (n=411). Low indicates the value below the median level (n=205) and high indicates values above the median level (n=206). The p value was calculated using a log-rank test

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