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Table 3 Cell division defects found in DOM-A depleted S2 cells

From: The ATPase SRCAP is associated with the mitotic apparatus, uncovering novel molecular aspects of Floating-Harbor syndrome

  

DomA

  

Mock (%)

RNAi (%)

Metaphase

MS

11.01 ± 2.48

46.33 ± 20.14***

CM

4.22 ± 4.58

20.9 ± 8.6***

Telophase

CB

0

3.81 ± 0.50**

LIB

1.57 ± 0.6

18.54 ± 13***

MC

1.16 ± 0.5

12.21 ± 3.84***

  1. CB, chromatin bridges; CM, chromosome misalignments; LIB, long intercellular bridges; MC, multinucleated cells; MS, multipolar spindles
  2. The results are expressed as mean ± SD values from three independent replicate experiments: *P < 0.05; **P < 0.005; and ***P < 0.0005 compared with the mock group by Fisher’s exact test