Fig. 3

Differential open chromatin accessibility analysis of A. niger. a Clustering analysis of ATAC-seq peaks for 16 A. niger samples. b Volcano plots of chromatin accessibility change combined with its annotated genes. ATAC_Fold means an increase (> 0) or decrease (< 0) in chromatin accessibility (X-axis). Y-axis represents the confidence coefficient of ATAC_fold. The red and green color points represent up- and downregulated genes with significance (|log2(Fold_Change)| ≥ 1, P < 0.05), respectively. c The overlap of peaks between PrtT ChIP-seq and ATAC-seq. d–f Visually display of the coupling analysis of ATAC-seq, ChIP-seq, and RNA-seq using IVG browser. The red vertical line indicates the PrtT binding site. The An number of target genes were labelled in the corresponding position