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Fig. 4 | BMC Biology

Fig. 4

From: Profiling of chromatin accessibility identifies transcription factor binding sites across the genome of Aspergillus species

Fig. 4

Effect of LaeA on the activity of secondary metabolism gene cluster in A. oryzae. a Scatter plot of differentially expressed genes (P < 0.05) and chromatin accessibility between A. oryzae WT strain and laeA mutants. Significantly differentially expressed SM genes (|log2(Fold_Change)| ≥ 1, P < 0.05) are indicated by red and purple dots. The green dotted line indicates |log2(Fold_Change)| = 1. All data are derived from two technical replicates. b A representative aflatoxin biosynthetic pathway in A. oryzae showing a comparison between ATAC-seq and RNA-seq for samples of A. oryzae WT strain and laeA mutants. OEleaA1, OElaeA2, dellaeA1, and dellaeA2 were biological replicates in RNA-seq and ATAC-seq analysis for the A. oryzae laeA mutants (OElaeA and dellaeA)

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