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Table 1 Model parameters used in simulations of infection unless otherwise specified

From: Generation of multicellular spatiotemporal models of population dynamics from ordinary differential equations, with applications in viral infection

Parameter

Value

Reference / justification

Infection rate β

7.18 × 10−13 s−1

Selected for complete infection by around 5 days

Eclipse phase parameter k

1.85 × 10−5 s−1

Selected for an eclipse phase of 15 h

Death rate d

2.78 × 10−6 s−1

Selected for complete cell death by around 21 days

Virus diffusion parameter DV

0.1 μm2 s−1

Selected to be 10× greater than value from [17] 1

Virus decay rate c

1.09 × 10−4 s−1

Selected for a diffusion length of approximately three cells

Virus production rate p

5.79 × 10−4 cell−1 s−1

Selected for complete infection by around 5 days

  1. 1 Estimates a range of [3 × 10−6 μm2/s, 3 μm2/s] based on Stokes-Einstein and steady-shear viscosity for SARS-CoV-2 in lung mucus