Table 3 Parameter values used in all simulations
Parameter | Value | Reference / justification |
|---|---|---|
Simulation step ∆t | 5 min./step | Selected for approx. 14 days of sim. time in 4 k sim. steps |
Lattice site width | 2 μm/site | Selected according to cell diameter |
Volume multiplier λv | 9 | [17] |
Volume constraint vc | 25 sites | Selected according to typical epithelial size and lattice site width |
Intrinsic random motility \( {\mathcal{H}}^{\ast } \) | 10 | [27] |
Global scaling coefficient η | 1.6 × 10−4 | Calculated from Eq. 12 according to model specifications |
Local scaling coefficient θ | 4 × 10−9 site−1 | Calculated from Eq. 17 according to model specification |