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Fig. 6 | BMC Biology

Fig. 6

From: Single-cell analysis at the protein level delineates intracellular signaling dynamic during hematopoiesis

Fig. 6

Signal proteins changes in BM subsets during hematopoietic recovery. A viSNE map displaying BM cells of all the mice (15,400 cells from each mouse). B viSNE maps colored by the normalized expression of the indicated markers. C viSNE map colored by 16 cell populations after clustering. D Bar plots showing the frequencies of BM cell subsets after different days of 5-FU treatment. p values were calculated with Student’s t test. E Bar plots showing the frequencies of the indicated protein positive cells in G-MDSCs from mice after different days of 5-FU treatment. p values were calculated with a one-way ANOVA followed by Tukey’s multiple comparisons test. F Schematic diagram showing the recovery process of BM cell subsets and the changed signaling proteins in each cell population after myelosuppression. n = 4 mice in each group. *p < 0.05, **p < 0.01, ***p < 0.001

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