Skip to main content
Fig. 5 | BMC Biology

Fig. 5

From: Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model

Fig. 5

Analysis of TCGA human samples with gene expression patterns similar to mouse cell groups. A MDS plot of mouse single-cell samples and such TCGA samples on the basis of a similarity of gene expression patterns. n = 42, 42, and 51 cells for the anti-epithelial, cGMP/GC, and dormant groups, respectively; n = 94, 42, and 13 TCGA samples for the anti-epithelial, cGMP/GC, and dormant types, respectively. B Heatmap of the samples. Genes are highly variable genes shown in Fig. 2C. The number of cells and cases are the same as in A. C The fraction of patients with metastatic tumor in TCGA samples with expression patterns similar to mouse cell groups

Back to article page