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Fig. 5 | BMC Biology

Fig. 5

From: Channel nuclear pore protein 54 directs sexual differentiation and neuronal wiring of female reproductive behaviors in Drosophila

Fig. 5

Nucleo-cytoplasmic shuttling is altered in Nup54QB62. A–M Cellular localization of nucleo-cytoplasmic shuttling RNA-binding protein ELAV (magenta) in representative control (A–F) and Nup54QB62/Df(2R)9B4 (G–L) expressing UASCD8GFP from ppkGAL4 (green). Arrowheads in A and G indicate the ppk expressing neuron in higher magnification for the control (B–E) and Nup54QB62/Df(2R)9B4 (G–K) and the line in E and K indicate the position where signal intensities (arbitrary units) were measured for GFP (green) and ELAV (magenta) plotted in F and L of a representative example (n=8). M Quantification of ELAV signals in nuclear and cytoplasmic cellular compartments in wild type and Nup54QB62/Df(2R)9B4 plotted as mean with the standard error of the ratio of the nuclear to the cytoplasmic signal (P≤0.0001). The scale bar in G is 50 μm and in K is 1 μm. The data underlying the presented graphs are in Additional file 6

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