Fig. 3

Most C3D is derived from nuclear DNA. A Size distributions of cfDNA fragments for the library prepared with the TACS-T4 scheme using cfDNA purified with the PPIP method are shown. Reads derived from nuclear (same data as in Fig. 2C), mitochondrial, and microbial genomic DNAs were separately analyzed. B Pie chart for the composition cfDNA reads in A. C Size distribution of cfDNA fragments in Burnham et al. (2016). D Pie chart for the composition cfDNA fragments in C. For details, see Supplementary Methods