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Table 1. Summary of binding regions in MIEF1/2 required for interactions with Drp1, Mfn1, Mfn2 and hFis1.

From: MIEF1/2 orchestrate mitochondrial dynamics through direct engagement with both the fission and fusion machineries

  1. Summary of potential protein binding regions in MIEFs required for Drp1, Mfn1, Mfn2 and hFis1 interactions identified by deletion mutants as presented in Figure 1. For the MIEF1Δ160-169 co-IP, see Fig 4B. Notice: -, +/-, +, ++ and +++ stand for the interaction from weakest to strongest as identified by co-IP followed by Western blotting.