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Fig. 1 | BMC Biology

Fig. 1

From: Long-term dynamics of the human oral microbiome during clinical disease progression

Fig. 1

Taxonomy and diversity profiling of the different clinical groups of teeth according to disease progression. a Temporal changes in the relative frequency of the most abundant common taxa (> 10%) among all groups at the species level. Counts were edgeR normalized. The vertical green line indicates the moment when patients received periodontal treatment. b Violin plot of Shannon α-diversity of all samples in the three different groups. Boxes span the first to third quartiles; the horizontal line inside the boxes represents the median, and black dots represent all samples in each group. Pairwise comparison is performed using the non-parametric Wilcoxon test, and p values are displayed. c Profiles of Shannon diversity across time. Error bars represent standard deviation. The vertical blue line indicates the moment when patients received periodontal treatment. d Rate of change of Shannon index over time. We calculated the first differences, which is the magnitude of change between successive time points, and represented them on a volatility plot. Error bars represent standard deviation

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