Fig. 5
From: Long-term dynamics of the human oral microbiome during clinical disease progression
Stability of the oral microbiome communities in the three different conditions. a–c Dirichlet process Gaussian process mixture model (DPGP) clusters of microbial species. Clusters are standardized to log2 fold-change of abundance. Colors and cluster numbers are arbitrary. The actual composition of the different clusters is presented in Additional File 8, Table S3. The grey zone represents the period after treatment. d Community stability aggregates species abundances within replicate and period and uses these values to calculate community stability as the temporal mean divided by the temporal standard deviation [26]. e Variance ratio calculated as the ratio of the community’s variance as a whole relative to the sum of the individual population variances. Bars represent the 95% confidence intervals after 1000 bootstraps. f Loreau and de Mazancourt synchrony metric comparing the variance of aggregated species abundances with the summed variances of individual species [27]