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Fig. 3 | BMC Biology

Fig. 3

From: Functional analyses of phosphatidylserine/PI(4)P exchangers with diverse lipid species and membrane contexts reveal unanticipated rules on lipid transfer

Fig. 3

Transfer of 18:1/18:0-PS vs 18:0/18:1-PS by Osh6p and ORD8. a Chemical structure of 18:1/18:0-PS compared to that of 18:0/18:0-PS and 18:0/18:1-PS. b Initial rates of PS and PI(4)P transfer, measured along opposite directions, between LA and LB liposomes (200 μM total lipid each) with Osh6p (200 nM) at 30 °C, in non-exchange or exchange contexts with 18:0/18:0-PS, 18:0/18:1-PS, or 18:1/18:0-PS (5% in LA liposomes) and 16:0/18:1-PI(4)P (5% in LB liposomes). Data are represented as mean ± s.e.m. (n = 3–4). c Similar experiments were performed with ORD8 (240 nM) at 37 °C using 18:1/18:1-PI(4)P instead of 16:0/18:1-PI(4)P

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