Fig. 2.From: Monkeying around with venom: an increased resistance to α-neurotoxins supports an evolutionary arms race between Afro-Asian primates and sympatric cobrasThe effects of venom from the Asian cobra Naja siamensis against the nAChR orthosteric site mimotopes from seven clades of primates (see additional file 1 for other Asian cobra species with congruent results). A Ancestral state reconstruction of the area under the curve (AUC) values of the binding of N. siamensis against the primate mimotopes. B Bar graphs represent the mean AUC values of the adjacent curve graphs. Statistical significance is indicated by matching letters with the colors of letter indicating the level of significance; brown p< 0.001, green p< 0.01, pink p< 0.05. C Curve graphs show the mean wavelength shift (nm) in light with binding of venoms over a 120-s association phase. The venom was tested in triplicate (n=3). Error bars on all graphs represent the SEM. AUC values were statistically analyzed using a one-way ANOVA with a Tukey’s comparisons multiple comparisons test comparing to the native mimotope. All raw data and statistical analyses outputs can be found in Additional file 2Back to article page