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Fig. 5 | BMC Biology

Fig. 5

From: Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle

Fig. 5

Summary of selection scan for mitonuclear selection signatures. A The diagram of selection scan process to detect mitonuclear selection signatures. B Population differentiation (Fst) between AFZ and ASZ or between AFZ and EUT/AST for each 10 kb window overlapping with N-mt genes. Each window is stratified by Fst quartiles divided based on Fst between EUT/AST and ASZ. The black dashed line indicates the mean Fst of each axis at each quartile. The black solid line indicates the linear regression. The red solid line indicates the threshold of the top 1% cutoff of Fst between AFZ and ASZ. C, D Selection signatures and genotypes in a selection candidate NDUFAF6 region. C Normalized XP-CLR (top), normalized nSL (middle), and weighted Fst (bottom) calculated for 10 kb non-overlapping windows in 1 Mb region adjacent to the candidate gene. D Weighted Fst, variant types, and genotypes at SNP loci is visualized for the candidate gene region. Missense variants and corresponding amino acid substitutions are marked with red arrows. SNP loci with minor allele frequency of 0.05 or lower are omitted. Individuals within each population are hierarchically clustered based on genotypes

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