From: Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle
Gene symbol | Window (chr:start-end) | normalized XP-CLR | normalized nSL | weighted Fst | Functional description |
---|---|---|---|---|---|
LYRM4 | 23:49320001-49330000 | 9.29 | 0.64 | 0.18 | To bind cysteine desulfurase and help free inorganic sulfur for Fe/S clusters |
COQ10A | 5:57390001-57400000 | 6.31 | 0 | 0.31 | Required for the function of coenzyme Q in the respiratory chain |
TOMM40L | 3:8290001-8300000 | 8.26 | 0 | 0.29 | To participate in the import of precursors into mitochondria as potential channel-forming protein |
FARS2 | 23:49010001-49020000 | 5.54 | 0.65 | 0.16 | To transfer phenylalanine to tRNA and to participate in mitochondria for mitochondrial protein translation |
MRPL41 | 11:105590001-105600000 | 8.98 | 0 | 0.35 | To participate in protein synthesis within the mitochondrion as ribosomal protein |
SCO1 | 19:30290001-30300000 | 7.01 | 0 | 0.26 | To incorporate two Cytochrome c oxidase subunits |
ABCB10 | 28:490001-500000 | 7.00 | 0.73 | 0.23 | To participate in transports of molecules across cellular membrane |
NDUFAF6 | 14:71630001-71640000 | 5.95 | 0.55 | 0.27 | To regulate of biogenesis of subunit ND1 that is crucial for assembly of the mitochondrial respiratory chain complex I |
IMMP2L | 4:57730001-57740000 | 5.18 | 0 | 0.28 | To process signal peptide sequences used to direct mitochondrial proteins to the mitochondria |
SPATA19 | 29:33750001-33760000 | 8.36 | 0.077 | 0.23 | Possibly to participate in spermiogenesis |
HSD3B1 | 3:23810001-23820000 | 6.16 | 0 | 0.27 | To catalyze the oxidative conversion of steroid precursors for the production of steroid hormones |
TRAK2 | 2:90350001-90360000 | 31.40 | 0.49 | 0.3 | Possibly to regulate endosome-to-lysosome trafficking of membrane cargo |
WWOX | 18:5720001-5730000 | 4.96 | 0.10 | 0.27 | To act as a tumor suppressor and to induce apoptosis |
SLC30A6 | 11:14780001-14790000 | 0 | 0.69 | 0.27 | To regulate cytoplasmic level of zinc |
MYH6 | 10:21350001-21360000 | 4.58 | 0 | 0.24 | To participate in muscle contraction |
CASP8 | 2:90290001-90300000 | 5.52 | 0.036 | 0.24 | To induce in apoptosis |
FYN | 9:39140001-39150000 | 4.02 | 0.27 | 0.36 | To control cell growth and survival as tyrosine kinase |
TMEM71 | 14:9630001-9640000 | 6.12 | 0 | 0.24 | Putative transmembrane protein |
PNPLA7 | 11:105600001-105610000 | 15.13 | 0 | 0.36 | To regulate adipocyte differentiation |
XAF1 | 19:25750001-25760000 | 9.76 | 0.24 | 0.29 | To regulate apoptosis by binds to the inhibitor of apoptosis protein family |
ZFHX3 | 18:38410001-38420000 | 5.58 | 0 | 0.29 | To regulate myogenic and neuronal differentiation. |