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Fig. 4 | BMC Biology

Fig. 4

From: Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality

Fig. 4

Synteny analysis of the gasdermin C and D loci from different species. Schematic diagrams showing the conserved synteny in the gsdmc loci (A) and gsdmd loci (B) in Mammalia (Homo sapiens, Mus musculus, Bos taurus). The synteny of the genes surrounding the mammalian gsdmc/d is shown in Aves (Gallus gallus), Amphibian (Xenopus tropicalis), Fish (Latimeria chalumnae, Danio rerio, Tetraodon nigroviridis), and Agnatha (Petromyzon marinus) to illustrate that no gsdmc or gsdmd is present in these species. Conserved genes are indicated in different colors, and the direction of gasdermin gene transcription is indicated with arrows. The position of the centromeres is indicated with a blue dot

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