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Fig. 7. | BMC Biology

Fig. 7.

From: Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality

Fig. 7.

Gene expression of gasdermin genes in different mouse tissues during sepsis. A Relative expression of mouse gsdma1, gsdmc, gsdmd, gsdme, pjvk, il6, and il1b genes analyzed by quantitative PCR from different tissues of sham operated mice (yellow) and septic mice (CLP, in orange). B Fold change of the expression of mouse gsdma1, gsdmc, gsdmd, gsdme, pjvk, il6, and il1b genes analyzed by quantitative PCR from different tissues of septic wild type (C57BL/6, in light green) versus Casp1/11-/- mice (dark green); Casp1/11-/- expression was relative to wild type expression. Each point represents an independent sample from n= 2 mice. Mann-Whitney test for A and B, *p<0.05

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