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Fig. 2 | BMC Biology

Fig. 2

From: Anaerobic derivates of mitochondria and peroxisomes in the free-living amoeba Pelomyxa schiedti revealed by single-cell genomics

Fig. 2

Overview of the Pelomyxa schiedti MRO metabolism. Proteins were identified by BLAST or HMMER searches, and their intracellular localization was predicted by TargetP, PSORT II, MultiLoc2, and NommPred tools. Confidence of MRO localization is enhanced by shades of blue as explained in graphical legend above the scheme. Multiple copies of a protein are shown as overlapping ovals. Proteins that localized in S. cerevisiae mitochondria (Fig. 3) are in bold and underlined. AAT, aspartate aminotransferase; ACO, aconitase; ACS, acetyl-CoA synthetase; AK, adenylate kinase; APS, adenosine-5′-phosphosulfate; APSK, adenosine-5′-phosphosulfate kinase; AS, ATP sulfurylase; cpn10, chaperonin 10; cpn60, chaperonin 60; CoA, coenzyme A; ETFa, electron transferring flavoprotein subunit alpha; ETFb, electron transferring flavoprotein subunit beta; ETFDH, electron transferring flavoprotein dehydrogenase; Fe-ADH, iron-containing alcohol dehydrogenase; Fd, ferredoxin; FdhD, formate dehydrogenase accessory sulfurtransferase; FH, fumarase; H, glycine cleavage system H protein; HSP70, heat shock protein 70; HydA, [FeFe]-hydrogenase; HydE, hydrogenase maturase; HydF, hydrogenase maturase; HydG, hydrogenase maturase; IPP, inorganic pyrophosphatase; L, glycine cleavage system L protein; LPLA, lipoamide protein ligase; MCF, mitochondrial carrier family; MDH, malate dehydrogenase; MPP a+b, mitochondrial processing peptidase subunit alpha and beta; NaS, sodium/sulfate symporter; NifS, cysteine desulfurase; NifU, scaffold protein; P, glycine cleavage system P protein; PAPS, 3′-phosphoadenosine 5′-phosphosulfate; PC, pyruvate carboxylase; PFO, pyruvate:ferredoxin oxidoreductase; PNT, pyridine nucleotide transhydrogenase; RQ, rodoquinone; RQH2, rhodoquinol; RquA, RQ methyltransferase; SAM, sorting and assembly machinery; SDH5, succinate dehydrogenase assembly factor; SDH5, succinate dehydrogenase assembly factor; SDHA, succinate dehydrogenase subunit A; SDHB, succinate dehydrogenase subunit B; SDHC, succinate dehydrogenase subunit C; SDHD, succinate dehydrogenase subunit D; SHMT, serine hydroxymethyltransferase; T, glycine cleavage system T protein; THF, tetrahydrofolate; THF-CH2, N5,N10-methylenetetrahydrofolate; TOM/TIM, translocase of outer/inner membrane; UQ, ubiquinone; Zn-ADH, zinc-containing alcohol dehydrogenase

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