Fig. 3

Gene family and phylogenetic analyses of Myxobolus honghuensis and other representative cnidarian genomes. Phylogenetic tree was generated from a matrix of 51 single-copy orthologs (11,323 amino acid positions) using maximum likelihood under the GTRGAMMA model. A Number of expanded (red) and contracted (blue) gene families in each evolutionary branch. The expanded families are related to energy metabolism, intra- and intercellular communication, and invasion. The contracted families are related to respiratory, neural, and immunity functions, e.g., cytochrome c biogenesis protein, immunoglobulin v-set domain, and clustered mitochondria. B Clusters of orthologous and paralogous gene families in M. honghuensis and 15 other cnidarians. C Overlap of gene families in M. honghuensis and four other myxozoans