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Fig. 4 | BMC Biology

Fig. 4

From: Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels

Fig. 4

EV-enriched transcripts and RBPs. A Enriched motifs from AME analysis in EV-enriched mRNA and lncRNA transcripts (padj < 0.1) relative to unchanged mRNA and lncRNA transcripts in 3 EV samples relative to 3 cell samples. RBP name, p-value and motif ID are shown. B Number of expressed and EV-enriched mRNA and lncRNA genes bound by HNRNPA2B1, as determined by HITS-CLIP. P-value determined by Fisher’s exact test. N = 16,249 expressed genes (11,825 mRNA and 4424 lncRNA), 652 EV-enriched genes (561 mRNA and 91 lncRNA). Individual values can be found in Additional file 17

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