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Fig. 4 | BMC Biology

Fig. 4

From: Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones

Fig. 4

Localization of EGR1 protein in the degenerating rd10 retina. Immunofluorescence against EGR1 (red) alone or in combination with OPN1SW (green) as a cone marker or RHO (green) as a marker for the perikarya of degenerating rods was performed in retinas of A, B wild-type controls, C–E rd10 at P21, F–H rd10 at P25, I–K rd10 at P28, L–N, Q rd10 at P35, and O, P rd10 at P59. DAPI (blue) was used as a nuclear stain. Scale bars: 50 μm. PS, photoreceptor segments; ONL, outer nuclear layer; INL, inner nuclear layer; IPL, inner plexiform layer; GCL, ganglion cell layer; WT, wild type

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