Fig. 4
From: Irisin mediates beiging of adipose-derived mesenchymal stem cells through binding to TRPC3
Analysis of the downstream signaling pathway after IRISIN stimulation. A, B Rosiglitazone induces differentiation of mesenchymal stem cells into beige fat cells. The cells are divided into two groups: the untreated group and the IRISIN-treated group. Chemiluminescence was analyzed using the AAH-MAPK-1 software. There was a significant change in the AKT, ERK, CREB, and P38MAPK, RSK1/2 signaling pathways. *p < 0.05, **p < 0.01, and ***p < 0.001