Fig. 5

Reduced insulin signalling predominately impacts I2 through M3. A Developmental rate of the wild-type and the mutants daf-2(e1370), daf-16(mu86) and daf-2(e1370);daf-16(mu86) at 12, 16, 20 and 22 °C. B Duration of each stage of development at 20 °C for the four strains. Each dot represents the value for a single animal. Developmental rate of intermolts (C) and molts (D) at 12, 16, 20 and 22 °C, for the wild-type and mutant strains. A–D Statistics show two-way ANOVA. All strains were compared to the wild-type, but only significant differences are shown