Fig. 7

The abundance and repeatability of USFs associated with Shank3-Het and KO rats correlate with their pitch. A Distributions of the sessions of each of the four genotypes examined based on the total number of USFs (excluding noise) that was detected in each session. B Proportions of sessions with more (red) or less (blue) than 600 USFs of all clusters for the Shank3-Het and KO rats and their WT littermates, analyzed separately for dyads of novel animals and cagemates. C Proportions of sessions categorized according to the number of USFs emitted during the session, separately calculated for each of clusters 4–16 of Shank3-Het, KO, and WT littermates (combining sessions of novel animals and cagemates). Note the gradual increase in the proportion of sessions with high numbers (>50) of USFs, specifically exhibited by Het and KO animals, for clusters 4–14. D Repeatability curves of each of the clusters shown in C, combined for Shank3-Het and KO animals. Note the gradual decrease in curve width with cluster number, for clusters of high-pitch USFs. E A statistically significant positive correlation was found between the number of sessions contributing to and the peak frequency of each of clusters 4–14, for Shank3-Het and KO rats, combined. F A statistically significant negative correlation was found between the half-width of the repeatability curve (shown in D) and peak frequency of each of clusters 4–14 for Het and KO animals, combined