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Fig. 6 | BMC Biology

Fig. 6

From: ASC proneural factors are necessary for chromatin remodeling during neuroectodermal to neuroblast fate transition to ensure the timely initiation of the neural stem cell program

Fig. 6

ASC loss is hard to compensate. Early and late rescue phenotypes of neuroectodermally (bibGal4) induced proneural targets in the Df(1)scB57 background. Early embryos (top row) stained with Dpn and Pros, late embryos (bottom row) stained with the axonal marker BP102. A Df(1)scB57; bibGal4 with no UAS transgene. BG as in A, plus B UAS-scrt, C UAS-wor, D UAS-dpn, E UAS-Oli, F UAS-ase, G UAS-scAPAA. H Model of ability of selected genes to rescue the Df(1)scB57 neuronal hypoplasia. I Model of ability of selected genes to induce neuronal hyperplasia in the wt background. Activators refer to ASC genes; repressors refer to Snail and Hes family genes. Effect is shown by a check mark; lack of effect by X

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