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Fig. 4 | BMC Biology

Fig. 4

From: Structure modeling hints at a granular organization of the Golgi ribbon

Fig. 4

Stable mini-stack dimers. A After secretory granule depletion by PMA, cells were allowed to replete their WPB pool in nocodazole. Size distributions of Golgi elements and WPBs were measured. B Electron micrographs of HUVECs treated with nocodazole for 24 h. Dispersed Golgi mini-stacks (dashed outline) were observed as monomers (left) or dimers (right); arrows point at forming WPBs; scale bars: 500 nm. C Predicted length distribution of WPBs (red stars), maintaining α constant between datasets, compared to real data (blue bars) in control (si-Luciferase) and different levels of VWF expressing cells (si-VWF); note: the higher the amount of siRNA targeting VWF, the lower its expression

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