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Table 1 Transcriptional changes with known tip-stalk localization identified in MAPK/ERK-deficient ureteric bud

From: Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney

UB-stalk-enriched genes upregulated in Mek1/2 dko Log2FC    UB-tip-enriched genes downregulated in Mek1/2 dko Log2FC
Atp6v0d2 5.82017 Paqr5 2.02776 Stmn1 − 1.0135
Thrb 5.68810 Neat1 1.99209 Rprm − 1.0289
Vsig1 4.44785 Cpeb2 1.94871 Frem2 − 1.0412
Trim47 4.07919 Dab2 1.93896 Ctnnd2 − 1.0942
Serpinb9 3.74231 Ppp1r3c 1.90854 Uhrf1 − 1.1082
Tmem117 3.59284 Itpr2 1.88864 Stra6 − 1.1199
Wdr72 3.58091 Akr1c19 1.86199 Gfra1 − 1.1478
Trim16 3.24198 Pdlim1 1.84855 Sema6a − 1.1662
Tspan8 3.23112 Scnn1a 1.83277 Kdm2b − 1.1890
Igf1 3.05885 Nr3c1 1.82302 Mycn − 1.2976
Cav1 3.04600 Igfbp7 1.72571 Slc27a6 − 1.3305
Muc20 3.02456 Elf5 1.69912 Fbln1 − 1.3432
Ccdc141 2.86843 Prlr 1.69734 Ung − 1.3621
Tmem45b 2.86742 Scnn1b 1.68607 Dctd − 1.3629
Gsta3 2.85412 Bmp3 1.67283 Sox8 − 1.4139
Nipal1 2.82231 Lypd6 1.63446 Nsg1 − 1.4406
Rhcg 2.80980 Slc29a1 1.63091 Cdca7 − 1.4578
Ugt2b34 2.69559 Ampd3 1.63017 Hs3st3b1 − 1.4741
Krt80 2.63243 Reps2 1.62458 Spred2 − 1.4753
Cers3 2.57988 Fam13a 1.57950 Acot7 − 1.5284
Foxa1 2.46191 Plxna2 1.57511 Fxyd6 − 1.5755
Anxa3 2.44622 Pde7b 1.53769 Fbln2 − 1.5889
Pde1a 2.41531 Dkk3 1.53697 Tmem59l − 1.6118
Acpp 2.40222 Atp1b1 1.52502 Spry4 − 1.6210
Slc40a1 2.37983 Meg3 1.46617 Ret − 1.7017
Slco2a1 2.36114 Foxq1 1.42632 Ror2 − 1.7602
Emp1 2.34928 AA986860 1.41052 Adamts18 − 1.8082
Fxyd4 2.22886 Parm1 1.34588 Ccnd1 − 1.8272
Pdzk1 2.19846 Slc7a8 1.31827 Cxcl14 − 1.9303
Cav2 2.14791 Itgb6 1.30563 Kank4 − 1.9339
Efemp1 2.14526 Rcan2 1.28463 Mfsd2a − 1.9530
Shh 2.13946 Tmprss2 1.25556 Ak1 − 1.9839
Pdzk1ip1 2.09042 Sparc 1.23359 Psmc3ip − 2.0363
Plcd1 2.08808 Krt7 1.20999 Etv4 − 2.1504
Efcab1 2.08737 Eno2 1.20676 Wnt11 − 2.1618
Aqp4 2.08663 Car12 1.19927 Psrc1 − 2.2083
Nr3c2 2.04846 Bmf 1.12381 Etv5 − 2.3936
1810019D21Rik 2.03767 Nedd4l 1.09804 Cib2 − 2.8918
Atp10b 2.03048 Cystm1 1.02906 Nrtn − 5.3538