Fig. 7

Nearest neighbor (NN) analysis for oligodendrocytes in P20 and P60 tissue sections. a For each cell, a region is plotted (tiles in the background), where all points of the region are closer to that cell than to any other (Voronoi tessellation). Each cell is a node in the graph and the edges connect the neighboring cells (Delaunay triangulation). A zoom-in is shown for the WM region. The main scale bar is 500 μm, and the zoom-in scale bar is 250 μm. b Heatmaps of the nearest neighbor likelihood (significant neighboring preferences highlighted by red boxes) and barplot of average distances to most prevalent NN for P20 CTX (top) and CC (bottom) (n = 6 P20 tissue sections). c Same as (b) for P60 CTX and CC (n = 6 P60 tissue sections). d Same as (a) for the spinal cord. The main scale bar is 100 μm, and the zoom-in scale bar is 50 μm. e Same as (b) for spinal cord P20 GM and WM (n = 6 P20 tissue sections). f Same as (e) for spinal cord P60 GM and WM (n = 6 P60 tissue sections)