Fig. 3

Morphological recovery of the NMJ postsynaptic domain during regeneration. Morphological parameters of the NMJ postsynaptic domain of LAL muscles were quantified 5, 15, 30, 60, and 90 days after nerve crush injury and in control mice. a–e AChR aggregates perimeter, endplate area, endplate perimeter, endplate diameter, and compactness of the postsynaptic domain. Drawings on top of each plot represent each of the measured parameters. The results are represented as the mean ± SEM and each individual value (N: 3–4 mice; 2 female plus 1–2 male mice). *p < 0.05, **p < 0.01, ****p< 0.0001, one-way ANOVA test. n.s. = non-significant