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Table 2 Cell division defects found in CRS-depleted HeLa cells

From: Evolutionary conserved relocation of chromatin remodeling complexes to the mitotic apparatus

   Mock Scramble BAF53a CFDP1 GAS41 MRG15 p400 Tip60 YL1
Metaphase MS 1.43 ± 1.47 0 ± 0 3.12 ± 3.35 0.43 ± 0.74 12.77 ± 3.13*** 3.23 ± 2.01 11.95 ± 0.74*** 10.77 ± 3.27*** 10.49 ± 2.80***
CM 2.03 ± 1.76 0.79 ± 1.37 29.00 ± 2.06*** 23.90 ± 6.11*** 31.60 ± 3.00*** 7.16 ± 1.85*(Scramble) 2.74 ± 0.85 29.80 ± 3.10*** 34.98 ± 4.72***
Telophase CB 0.87 ± 1.52 0.56 ± 0.98 15.86 ± 0.57*** 30.16 ± 1.96*** 1.80 ± 0.97 4.13 ± 0.95*** 1.29 ± 0.14 4.55 ± 3.75*** 1.83 ± 0.39
LIB 0.44 ± 0.20 0.62 ± 0.30 30.27 ± 2.79*** 0.57 ± 0.51 9.41 ± 1.54*** 3.19 ± 1.74*** 0.84 ± 0.36 4.88 ± 2.75*** 8.32 ± 3.29***
MC 1.40 ± 1.03 1.55 ± 1.21 5.96 ± 0.90*** 4.02 ± 1.99*** 2.89 ± 0.90*** 6.87 ± 1.36*** 4.98 ± 0.89*** 3.09 ± 1.27*** 2.47 ± 0.65***
  1. MS multipolar spindles, CM chromosome misalignments, CB chromatin bridges, LIB long intercellular bridges, MC multinucleated cells
  2. The results are expressed as mean ± SD values from three independent replicate experiments. Experimental groups were compared with control groups (mocks and scrambles) by Fisher’s exact test. *=P < 0.05; **P= < 0.005; and ***=P < 0.0005
  3. *(Scramble)=This means that it is statistically significant only with the scramble