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Table 4 Treatment with ZM447439 (ZM) and Barasertib (BS) inhibitors

From: Evolutionary conserved relocation of chromatin remodeling complexes to the mitotic apparatus

 

DMSO (ZM)

ZM447439

DMSO (BS)

Barasertib

Aurora B

0.00 ± 0.00

0.00 ± 0.00

2.81 ± 1.14

10.00 ± 0.00*

MKLP1

2.34 ± 3.21

32.68 ± 0.87***

7.50 ± 4.95

21.00 ± 4.24***

BAF53a

5.67 ± 2.08

16.00 ± 5.00***

6.50 ± 0.71

24.50 ± 4.95***

Tip60

2.58 ± 1.37

42.00 ± 3.00***

4.78 ± 1.48

30.34 ± 2.50***

SRCAP

0.34 ± 0.58

1.33 ± 2.31

0.48 ± 0.67

1.43 ± 0.71

  1. The results are expressed as mean ± SD values from three independent replicate experiments
  2. Experimental groups were compared with DMSO-treated controls by Fisher's exact test. *=P <0.05; **=P < 0.005; and ***=P < 0.0005
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BMC Biology

ISSN: 1741-7007

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