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Table 4 Treatment with ZM447439 (ZM) and Barasertib (BS) inhibitors

From: Evolutionary conserved relocation of chromatin remodeling complexes to the mitotic apparatus

  DMSO (ZM) ZM447439 DMSO (BS) Barasertib
Aurora B 0.00 ± 0.00 0.00 ± 0.00 2.81 ± 1.14 10.00 ± 0.00*
MKLP1 2.34 ± 3.21 32.68 ± 0.87*** 7.50 ± 4.95 21.00 ± 4.24***
BAF53a 5.67 ± 2.08 16.00 ± 5.00*** 6.50 ± 0.71 24.50 ± 4.95***
Tip60 2.58 ± 1.37 42.00 ± 3.00*** 4.78 ± 1.48 30.34 ± 2.50***
SRCAP 0.34 ± 0.58 1.33 ± 2.31 0.48 ± 0.67 1.43 ± 0.71
  1. The results are expressed as mean ± SD values from three independent replicate experiments
  2. Experimental groups were compared with DMSO-treated controls by Fisher's exact test. *=P <0.05; **=P < 0.005; and ***=P < 0.0005