Fig. 6
From: Hmga2 protein loss alters nuclear envelope and 3D chromatin structure
3D genome structure in wt and Hmga2 KO cells. A Left: Genome-wide Hi-C data in wt and Hmga2 KO conditions at 5Mb resolution, right: Hi-C data of chromosome 11 in both conditions at 250Kb resolution. B Hi-C maps in the region chr11:105000000-116000000, 25-Kb resolution. Insulation score and boundaries are reported below. C Overlap between boundaries (detected at 50kb resolution) in wt and Hmga2 KO for chromosome 11. D Enrichment in WT of H3K4me3, H3K27me3, and Hmga2 (normalized) at TAD boundaries, shaded area represents the standard error of each point