Fig. 6
From: Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium
Effect of CDZ binding on calmodulin. CDZ binding dramatically affects the conformation of CaM, which collapses from a dumbbell-shaped conformation into a compact globular structure in which the CaM lobes wrap around CDZ. A single CDZ molecule is enough to induce dynamics and structural changes of CaM. The N-lobe and C-lobe of holo-CaM are depicted in blue and red, respectively