Fig. 2

Comparative analysis of the structure and chromosomal location of genes encoding kisspeptin-type receptors. A Comparison of the exon/intron structure of genes encoding kisspeptin-type receptors in A. rubens (Ar), Homo sapiens (Hs), Xenopus tropicalis (Xt), Lepisosteus oculatus (Lo), and Crassostrea gigas (Cg). Exons are shown as rectangles, with non-coding regions white and protein-coding regions black or colored (regions encoding predicted transmembrane domains 1–7 are shown in red, orange, yellow, green, blue, dark purple, and light purple, respectively). Introns are shown as lines, with length underneath. The two introns highlighted with a pink bracket are a conserved feature (see also Additional file 9). Accession numbers for the transcripts/genes represented in this figure are in Additional file 2. B Diagram showing the chromosomal locations of genes encoding ArKPR1-11 in A. rubens. Genes encoding (i) ArKPR1-4, (ii) ArKPR5-9; ArKPR11, and (iii) ArKPR10 are located on chromosomes 15, 10, and 4, respectively. Curved lines linking genes correspond to clades in Fig. 1: light purple is clade 1, green is clade 3.1, orange is clade 3.2, and black is clade 3.3. C Diagram showing the relative locations and orientations of genes encoding (i) ArKPR1-4 (clade 1 and 2 of Fig. 1) in a region of chromosome 15, (ii) ArKPR5-7 (clade 3.2 of Fig. 1) in a region of chromosome 10, (iii) ArKPR8-9 (clade 3.1 and 3.3 of Fig. 1) in a region of chromosome 10, and (iv) ArKPR10 (clade 3.3 of Fig. 1). The length (including exons and introns) and orientation of the genes is indicated by the purple arrows and the distance between genes (number of bases) is stated underneath the intervening black lines. The absence (0 genes) or presence (number of genes) of other genes in between those encoding the kisspeptin-type receptors is also stated (see Additional file 11 for data)