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Fig. 5 | BMC Biology

Fig. 5

From: Accurate prediction of functional states of cis-regulatory modules reveals common epigenetic rules in humans and mice

Fig. 5

Common epigenetic rules defining functional states of CRMs in various cell/tissue types of the same and different species. A, B Boxplots of AUROCs of the models trained and tested in the same cell/tissue types in human (A) or mouse (B), of the models trained in multiple cell/tissue types in human (A) or mouse (B) and tested in different cell/tissue types in the same species, and of the model trained in multiple cell/tissue types in mouse (A) or human (B) and tested in various cell/tissue types in human or in mouse, respectively. The statistical tests were done using Wilcoxon signed-rank test. C, D Boxplots of coefficients of the four marks in the LR models trained in multiple cell/tissue types in human (C) or mouse (D) and tested in different cell/tissue types in the same species. **p<0.001 (Wilcoxon signed-rank test), the weights of CA are significantly higher than those of the other three marks. E, F Coefficients of the four marks in the model trained in multiple cell/tissue types of mouse (E) or human (F) and tested in various cell/tissue types of human or mouse, respectively

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