Fig. 6

Identification of DSBR cases by capturing single-cell variability. a Heat maps of individual wells per experimental condition: Each row per map represents data from an individual well, and the wells are ranked vertically in each map from those with least to most of cells at \(t=24\) h (see arrows on the left side). For each condition, from left to right: \(\log _{10}(N^\text{local}_\text {tot}\)), \(\log _{10}(N^\text{local}_\text {GFP}\)), and \(R^\text {local}\). The color scales highlight extreme values near the \(10\text{th}\) and \(90\text{th}\) percentiles. In \(N_\text{local}^\text{GFP}\) maps, the black line indicates the first division time \(t_{\text {lag}}\). b Cartoons of the three identified behaviors: high-efficacy error-free repair, normal cell growth (first panel); low-efficacy error-free repair, normal cell growth (middle panel); and low-efficacy error-prone repair, impaired cell growth (third panel)