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Fig. 1 | BMC Biology

Fig. 1

From: A bacteria-regulated gut peptide determines host dependence on specific bacteria to support host juvenile development and survival

Fig. 1

Differential effects of the Imp-L2 host gene mutation on the development-promoting effects of Lp and Ap. a Mono-association of germ-free (GF) wild-type (WT) larvae with Lp (WJL) advances the pupariation timing, but mono-association of GF larvae of Imp-L2 mutants with Lp (WJL) does not advance the pupariation timing. b Mono-association of GF WT larvae with Ap (DM001) or P3G5 advances the pupariation timing. The advancing effect of P3G5 is weaker than that of Ap (DM001) as reported previously. Mono-association of GF larvae of Imp-L2 mutants with Ap (DM001) or P3G5 advances the pupariation timing similarly to WT. c Similar loads of Lp (WJL), Ap (DM001), and P3G5 in the guts of WT and Imp-L2 mutant larvae. Bacterial load in the 2nd and mid-3rd instar larval gut is shown by the colony-forming units (CFUs). Pupariation times are normalized to those of the GF larvae, taken as 1.0. Values shown are obtained from more than three independent observations. *p < 0.05 and **p < 0.01 compared to values from GF larvae (t-test). n.s., not statistically significant. Error bars denote standard error of the mean (SEM)

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