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Fig. 1 | BMC Biology

Fig. 1

From: Comparative epigenomics reveals the impact of ruminant-specific regulatory elements on complex traits

Fig. 1

Summary and characterization of 137 epigenetic and gene expression data in six mammals. A Datasets analyzed by this study. B The number of regulatory regions (promoters and enhancers) identified in the liver of each species. C Fold enrichments of regulatory elements (REs) for 14 chromatin states previously predicted in cattle and pig liver [19]. These chromatin states mainly represented enhancers (CTCF/Enhancer, Active_Enhancer, and Primed_Enhancer), promoters (CTCF/Promoter, Active_Promoter, Promoter, Poised_Promoter), repressed regions (Insulator, Low_Signal, and Polycomb_Repressed), open regions (Active_Element), and TSS-proximal regions (CTCF/TSS, Active_TSS, and Flanking TSS). D The percentages of REs overlapped with public data in cattle liver (blue) and newly annotated in this study (orange). E The sample clustering based on pairwise Spearman correlation of gene expression. F Similarity of sample clustering patterns across different omics data types using Rand index

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