Skip to main content
Fig. 2 | BMC Biology

Fig. 2

From: Comparative epigenomics reveals the impact of ruminant-specific regulatory elements on complex traits

Fig. 2

Evolutionary changes of regulatory elements (REs) and gene expression across mammals. Phylogenetic trees were built using the neighbor-joining method for gene expression of 9796 one-to-one orthologous genes (A), H3K27ac signals (B), H3K4me3 signals (C), chromatin accessibility (D), and DNA methylation level (E) in REs (enhancers and promoters) of orthologous genes. F Comparisons of total branch lengths of the phylogenetic trees across five omics data types using 1000 bootstrapping test. “****” indicates P < 0.0001

Back to article page