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Fig. 7 | BMC Biology

Fig. 7

From: Comparative epigenomics reveals the impact of ruminant-specific regulatory elements on complex traits

Fig. 7

A cattle-specific enhancer of DGAT1 was associated with protein percentage in cattle. A The top panel is the Manhattan plot of protein percentage in cattle [3]. The bottom panel shows H3K27ac (green) and H3K4me3 (purple) profiles within the DGAT1 locus across six species. B H3K27ac (green) and H3K4me3 (purple) profiles within the DGAT1 locus across eight tissues in cattle. C The PEER-corrected expression level of DGAT1 is significantly associated with three genotypes of rs384957047 in cattle liver [9]. D The relative luciferase activity of the recombinant plasmids constructed with DGAT1_T and DGAT1_C of rs384957047. “**” indicates P < 0.01; “***” indicates P < 0.001

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