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Fig. 6 | BMC Biology

Fig. 6

From: Folate regulates RNA m5C modification and translation in neural stem cells

Fig. 6

Correlation between m5C methylation and mRNA translation. a–c Heatmap showing the methylation profile of differentially methylated m5C sites in the comparison between total and polysome mRNAs. d–f Volcano plot showing the differentially expressed genes (DEGs) in the comparison between total and polysome mRNAs. g–i Distribution of mRNAs with a significant change in m5C methylation level in three categories: positive correlation, negative correlation, and neutral correlation between m5C methylation and mRNA translation efficiency. j Stacked bar charts showing the distribution of sites in different m5C methylation-mRNA translation correlation categories. k A summary table showing the transcripts with consistently positive/negative/neutral correlations between m5C methylation and mRNA translation among the three conditions.

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