Fig. 10

Sleep and sleep deprivation in elav > linker (red, n = 181) flies and relative controls [elav/+ (black, n = 118) and linker/+ (blue, n = 212)]. A 24 h sleep profile, plotted as time asleep within 30 min bins, over the day (grey, lights off; white, lights on). B–D Total sleep quantification over the 24 h (B), during light (C) and dark (D) periods. E Sleep stability calculated as maximum sleep minus maximum wake duration. F–H Number of sleep episodes over the 24 h (F), during light (G) and dark (H) periods. I–K Mean duration of sleep episodes over the 24 h (I), during light (J) and dark (K) periods. L Sleep latency. Kruskal-Wallis followed by Dunn’s multiple comparisons, ***p < 0.001. M Sleep profile after 12 h of SD. N Total sleep quantification over the 24 h baseline (BSL) and for the day after SD. O Number of sleep episodes over the 24 h BSL and after SD. P Duration of sleep episodes over the 24 h BSL and after SD. Kruskal-Wallis’s test for genotype effect, Wilcoxon’s test for pair-wise comparisons, *p < 0.05, ***p < 0.001