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Fig. 7 | BMC Biology

Fig. 7

From: CD4+ and CD8+ regulatory T cell characterization in the rat using a unique transgenic Foxp3-EGFP model

Fig. 7

IL-2 induce expansion of EGFP+ Tregs in vivo. Foxp3-EGFP rats received or not hIL-2 and the percent of the indicated cell populations was analyzed in blood. A Percentages of cells in the indicated cell populations out of T cells for CD4+ and CD8+ cells and total cells for CD161 cells of IL-2-treated and untreated rats. Left graph shows mean ± SEM, n = 3, and right contour plots show a representative animal. B Percentage and MFI (left and middle histograms, respectively) of pStat5+ cells in the indicated cell populations in IL-2-treated and untreated rats (mean ± SEM, n = 4 or 3). Middle contour plots show a representative animal. C Percentage and MFI (left and middle histograms, respectively) of CD25+ cells in the indicated cell populations of IL-2-treated and untreated rats (mean ± SEM, n = 4 or 3). Middle contour plots show a representative animal

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