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Fig. 3 | BMC Biology

Fig. 3

From: Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains

Fig. 3

Thermal and chemical stability of IgLCs. A Thermal unfolding of P007 (as an example) at 103, 52, 26 and 13 μM followed by intrinsic fluorescence. In addition, the evolution of the distribution of hydrodynamic radii is shown as a function of temperature as a contour plot (full data set with all samples in Additional file 2: Fig. S1. Contours are spaced with 0.1 and the lowest contour drawn is at 0.03 amplitude. B Combined chemical and thermal unfolding of P007 (as an example) at 20 μM and urea concentrations of 0 to 5.36 M in 8 steps (full data set with all samples in Additional file 2: Fig. S2)

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BMC Biology

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