Fig. 4

Genetic map of the brain bacterium genome. A The heatmap shows distribution of the DNA of the brain NTM in the mummy’s samples as well as other control samples; The numbers to the left refer to the sample ID as referred to in Additional file 1: Table S1, while the letters refer to the samples group as follows: S, the mummy’s tissue samples; C1, control samples that were in contact with the mummy; C2, samples that were taken from other individuals from the same burial site; C3, soil sample that was collected from inside the coffin of the mummy (please refer to Additional file 1: Table S1 and Additional file 2: Figure S4 for further details). The presence is shown by breadth values with minimum coverage of 3x per site. The contigs are arranged in a descending order from left to right (for details on the contigs, please refer to Additional file 1: Table S5). The loci referred to in bold red fonts are gene clusters/operons and are further detailed in Additional file 2: Figure S5, while those in black bold are genes that are known to be involved in crossing blood brain barrier (BBB) and brain invasion. B The genetic map of the contig 38, which is assumed to be a phage genome, as inferred by the tool PHASTER (for further details on the phage annotation, please refer to Additional file 1: Table S7)